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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">108451</article-id><article-id pub-id-type="doi">10.26442/20751753.2022.2.201521</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Progression of neurosyphilis in a patient with HIV-infection. Case report</article-title><trans-title-group xml:lang="ru"><trans-title>Прогрессирование нейросифилиса у пациента с ВИЧ-инфекцией. Клинический случай</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8201-2376</contrib-id><name-alternatives><name xml:lang="en"><surname>Kuznetsov</surname><given-names>Denis V.</given-names></name><name xml:lang="ru"><surname>Кузнецов</surname><given-names>Денис Владимирович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>neurologist, Moscow Scientific and Practical Center of Dermatology, Venereology and Cosmetology</p></bio><bio xml:lang="ru"><p>врач-невролог ГБУЗ МНПЦДК</p></bio><email>doktor.nevrolog@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1158-2486</contrib-id><name-alternatives><name xml:lang="en"><surname>Kudryavtseva</surname><given-names>Lyudmila E.</given-names></name><name xml:lang="ru"><surname>Кудрявцева</surname><given-names>Людмила Евгеньевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>dermatologist, Moscow Scientific and Practical Center of Dermatology, Venereology and Cosmetology</p></bio><bio xml:lang="ru"><p>врач-дерматовенеролог ГБУЗ МНПЦДК</p></bio><email>liudmila.kudriavtsieva@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6583-0318</contrib-id><name-alternatives><name xml:lang="en"><surname>Korsunskaya</surname><given-names>Irina M.</given-names></name><name xml:lang="ru"><surname>Корсунская</surname><given-names>Ирина Марковна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>D. Sci. (Med.), Prof., Center for Theoretical Problems of Physical and Chemical Pharmacology</p></bio><bio xml:lang="ru"><p>д-р мед. наук, проф., зав. лаб. физико-химических и генетических проблем дерматологии ФГБУН ЦТП ФХФ</p></bio><email>marykor@bk.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Moscow Scientific and Practical Center of Dermatology, Venereology and Cosmetology</institution></aff><aff><institution xml:lang="ru">ГБУЗ «Московский научно-практический центр дерматовенерологии и косметологии» Департамента здравоохранения г. Москвы</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Center for Theoretical Problems of Physical and Chemical Pharmacology</institution></aff><aff><institution xml:lang="ru">ФГБУН «Центр теоретических проблем физико-химической фармакологии» РАН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2022</year></pub-date><volume>24</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>128</fpage><lpage>131</lpage><history><date date-type="received" iso-8601-date="2022-06-01"><day>01</day><month>06</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-06-01"><day>01</day><month>06</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/108451">https://consilium.orscience.ru/2075-1753/article/view/108451</self-uri><abstract xml:lang="en"><p>In recent years, the incidence of syphilis, including neurosyphilis, has been increasing worldwide. In our practice, we have noticed an increase in the number of patients who were not examined for the specific pathologies associated with syphilis in timely manner. Given the variety of clinical manifestations of syphilis and the change in the course of the disease associated with HIV-infection, we described the observation of a patient with rapidly progressing (up to the development of a gummous form) neurosyphilis. The clinical case is intended to drag the attention of specialists to necessity to inform patients about the possible consequences of their disease and importance of thorough diagnosis by related specialists.</p></abstract><trans-abstract xml:lang="ru"><p>В последние годы заболеваемость сифилисом, в том числе и нейросифилисом, во всем мире возрастает. В своей практике мы отмечаем увеличение числа пациентов, которые не были своевременно обследованы на наличие специфических патологий, связанных с сифилисом. Учитывая разнообразие клинических проявлений сифилиса и изменение течения заболевания на фоне ВИЧ-инфекции, мы сочли целесообразным привести описание наблюдения за пациентом с быстропрогрессирующим (вплоть до развития гуммозной формы) нейросифилисом. Описанный случай призван обратить внимание врачей на необходимость информирования пациентов о возможных последствиях их заболевания и важность тщательной его диагностики смежными специалистами.</p></trans-abstract><kwd-group xml:lang="en"><kwd>neurosyphilis</kwd><kwd>HIV-infection</kwd><kwd>gummous form of neurosyphilis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>нейросифилис</kwd><kwd>ВИЧ-инфекция</kwd><kwd>гуммозная форма нейросифилиса</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Hobbs E, Vera JH, Marks M, et al. Neurosyphilis in patients with HIV. Pract Neurol. 2018;18(3):211-8. 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