Consilium MedicumConsilium MedicumConsilium MedicumConsilium Medicum2075-17532542-2170Consilium Medicum63423310.26442/20751753.2024.8.202909ArticlesСтатьиReview ArticleAdalimumab: A key element in the treatment strategy for immune-mediated inflammatory diseases: A reviewАдалимумаб: ключевой элемент в стратегии лечения иммуноопосредованных воспалительных заболеванийhttps://orcid.org/0009-0002-3078-6270GilavianMariam A.ГилавянМариам Артуровна
Russian Federation

Student

студентка

gilavyan_m_a@student.sechenov.ruhttps://orcid.org/0009-0002-3955-5807TrunovaDaria V.ТруноваДарья Васильевна
Russian Federation

Student

студентка

gilavyan_m_a@student.sechenov.ruhttps://orcid.org/0009-0008-1158-9697UstinovaAnastasia V.УстиноваАнастасия Витальевна
Russian Federation

Student

студентка

gilavyan_m_a@student.sechenov.ruhttps://orcid.org/0000-0002-8687-8521SukhanovaAnna M.СухановаАнна Михайловна
Russian Federation

Cand. Sci. (Pharmaceut.)

канд. фарм. наук, ст. преп. каф. фармацевтической и токсикологической химии им. А.П. Арзамасцева

gilavyan_m_a@student.sechenov.ruSechenov First Moscow State Medical University (Sechenov University)ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)06102024268Dermatology and allergologyДерматология и аллергология4924971207202418072024Copyright ©; 2024, Consilium MedicumCopyright ©; 2024, ООО "Консилиум Медикум"2024Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://consilium.orscience.ru/2075-1753/article/view/634233

Adalimumab is a biological drug effectively used in the treatment of several immune-mediated inflammatory diseases, including ankylosing spondylitis, juvenile idiopathic arthritis, and psoriasis. This study analyzed the therapeutic and economic benefits of adalimumab. Patients with ankylosing spondylitis showed significant improvements in quality of life and work productivity after treatment with adalimumab, confirming its clinical and economic efficacy. In the case of juvenile idiopathic arthritis and psoriasis, adalimumab demonstrated high efficacy and safety, significantly improving patients' conditions, establishing it as the gold standard of therapy. The use of adalimumab biosimilars offers accessible alternatives to the original drugs, expanding treatment options and reducing the economic burden on patients.

Адалимумаб – биологический препарат, который эффективно используется в лечении иммуноопосредованных воспалительных заболеваний, таких как анкилозирующий спондилит, ювенильный идиопатический артрит и псориаз. В данном исследовании подробно проанализированы терапевтические и экономические преимущества адалимумаба. У пациентов с анкилозирующим спондилитом наблюдались значительные улучшения в качестве жизни и производительности труда после лечения адалимумабом, что подтверждает его клиническую и экономическую эффективность. При лечении псориаза и ювенильного идиопатического артрита адалимумаб продемонстрировал высокую эффективность и безопасность, значительно улучшая состояние пациентов, что сделало его «золотым стандартом» терапии. Кроме того, биоаналоги адалимумаба – это более доступные альтернативы оригинальным препаратам, расширяющие возможности лечения и уменьшающие экономическое бремя пациентов. Полученные результаты подчеркивают важность применения адалимумаба в современной медицине и его значительный вклад в улучшение качества жизни пациентов с хроническими воспалительными заболеваниями.

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