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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">91759</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Khronicheskaya dykhatel'naya nedostatochnost'</article-title><trans-title-group xml:lang="ru"><trans-title>Хроническая дыхательная недостаточность</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Avdeev</surname><given-names>S. N</given-names></name><name xml:lang="ru"><surname>Авдеев</surname><given-names>С. Н</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">НИИ пульмонологии МЗ и СР РФ, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2004-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2004</year></pub-date><volume>6</volume><issue>4</issue><issue-title xml:lang="en">VOL 6, NO4 (2004)</issue-title><issue-title xml:lang="ru">ТОМ 6, №4 (2004)</issue-title><fpage>263</fpage><lpage>269</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2004, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2004, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/91759">https://consilium.orscience.ru/2075-1753/article/view/91759</self-uri><abstract xml:lang="ru"><p>В настоящее время существует несколько распространенных определений дыхательной недостаточности. Одним из наиболее распространенных является следующее определение: Дыхательная недостаточность (ДН) - неспособность системы дыхания обеспечить нормальный газовый состав артериальной крови [1, 2]. Другим, более практичным, является следующее определение: ДН - патологический синдром, при котором парциальное напряжение кислорода в артериальной крови (РаО 2) меньше 60 мм рт.ст. и/или парциальное напряжение углекислого газа (РаСО 2) больше 45 мм рт.ст. “Золотым стандартом” оценки ХДН является газовый анализ артериальной крови. Важнейшими показателями являются РаО 2, РаСО 2, рН и уровень бикарбонатов (НСО3-) артериальной крови, причем серийное или динамическое исследование этих показателей имеет большее значение, чем однократный анализ. Обязательным критерием ХДН является гипоксемия. Очень редко удается радикально изменить течение ХДН, хотя в последнее время и это стало возможным благодаря развитию трансплантации легких (при ХОБЛ, интерстициальном легочном фиброзе, муковисцидозе и др.). Приоритетом терапии больных с ХДН является выявление и устранение потенциально обратимых факторов, вносящих вклад в прогрессирование и “утяжеление” ХДН.</p></abstract><kwd-group xml:lang="ru"><kwd>дыхательная недостаточность</kwd><kwd>диспноэ</kwd><kwd>газообмен</kwd><kwd>гипоксемия</kwd><kwd>вентиляция легких</kwd><kwd>реабилитация</kwd><kwd>терапия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Зильбер А.П. Дыхательная недостаточность. М.: Медицина, 1989.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Davidson C, Treacher D. Respiratory Critical Care. London, Arnold, 2002.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Campbell E.J.M. Am Rev Respir Dis 1967; 96: 626-39.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Adrogue H.J, Tobin M.J. Respiratory failure. 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