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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">92022</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Ftorkhinolony v lechenii bol'nykh lekarstvenno-ustoychivym tuberkulezom legkikh</article-title><trans-title-group xml:lang="ru"><trans-title>Фторхинолоны в лечении больных лекарственно-устойчивым туберкулезом легких</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chukanov</surname><given-names>V. I</given-names></name><name xml:lang="ru"><surname>Чуканов</surname><given-names>В. И</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vasil'eva</surname><given-names>I. A</given-names></name><name xml:lang="ru"><surname>Васильева</surname><given-names>И. А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vaniev</surname><given-names>E. V</given-names></name><name xml:lang="ru"><surname>Ваниев</surname><given-names>Э. В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ГУ Центральный НИИ туберкулеза РАМН, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2005-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2005</year></pub-date><volume>7</volume><issue>10</issue><issue-title xml:lang="en">VOL 7, NO10 (2005)</issue-title><issue-title xml:lang="ru">ТОМ 7, №10 (2005)</issue-title><fpage>854</fpage><lpage>856</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2005, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2005, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2005</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/92022">https://consilium.orscience.ru/2075-1753/article/view/92022</self-uri><abstract xml:lang="ru"><p>Настоящее положение с лекарственно-устойчивым туберкулезом в России вызывает серьезную озабоченность фтизиатров. Особенностью современной эпидемической ситуации является рост частоты не только вторичной, обусловленной неправильным или неконтролируемым лечением, но и первичной лекарственной устойчивостью. Именно этот фактор считается основным среди причин терапевтических неудач.В этой связи остро стоит проблема поиска эффективных противотуберкулезных препаратов, к которым МБТ сохранили чувствительность. Наиболее перспективной для лечения резистентных форм туберкулеза является группа препаратов фторхинолонового ряда, активные свойства которой по отношению к M. tuberculosis описаны многими авторами.Суммируя результаты проведенных исследований по изучению эффективности различных схем химиотерапии туберкулеза как у впервые выявленных больных с первичной резистентностью МБТ, так и у ранее леченных с множественной лекарственной устойчивостью, следует отметить явное преимущество резервных режимов терапии с включением в них препарата фторхинолонового ряда.</p></abstract><kwd-group xml:lang="ru"><kwd>лекарственно-устойчивый туберкулез</kwd><kwd>противотуберкулезные препараты</kwd><kwd>фторхинолоны</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Хоменко А.Г., Чуканов В.И., Корнеев А.А. Эффективность химиотерапии туберкулеза легких с лекарственно - устойчивыми микобактериями. 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