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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">92127</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Osnovnoy podkhod k farmakoterapii metabolicheskogo sindroma</article-title><trans-title-group xml:lang="ru"><trans-title>Основной подход к фармакотерапии метаболического синдрома</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mkrtumyan</surname><given-names>A. M</given-names></name><name xml:lang="ru"><surname>Мкртумян</surname><given-names>А. М</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра эндокринологии и диабетологии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Biryukova</surname><given-names>E. V</given-names></name><name xml:lang="ru"><surname>Бирюкова</surname><given-names>Е. В</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра эндокринологии и диабетологии</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">МГМСУ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2006-05-15" publication-format="electronic"><day>15</day><month>05</month><year>2006</year></pub-date><volume>8</volume><issue>5</issue><issue-title xml:lang="en">VOL 8, NO5 (2006)</issue-title><issue-title xml:lang="ru">ТОМ 8, №5 (2006)</issue-title><fpage>54</fpage><lpage>58</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2006, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2006, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2006</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/92127">https://consilium.orscience.ru/2075-1753/article/view/92127</self-uri><abstract xml:lang="ru"><p>В клинической практике врачи различных специальностей довольно часто сталкиваются с метаболическим синдромом (МС), который представляет собой кластер гормональных и метаболических нарушений, объединенных общим патофизиологическим механизмом – инсулинорезистентностью (ИР). Актуальность проблемы МС в современной медицине вызвана прежде всего большим медико-социальным значением.Следует отметить, что эффективность лечения МС, как и любого хронического состояния, тесно связана с его продолжительностью и достижения максимальных положительных результатов терапии можно ожидать на начальных стадиях его развития. В связи с этим понятны приоритеты ранней диагностики МС для врачей широкой клинической практики.При коррекции АГ у больных с МС необходимо добиваться полной нормализации АД. Наиболее важным требованием при выборе гипотензивной терапии является отсутствие отрицательного метаболического действия препарата. Коррекция дислипидемий проводится как статинами, так и фибратами, основной целью которой является достижение оптимальных параметров липидного обмена. Выбор гиполипидемической терапии зависит от конкретной ситуации.</p></abstract></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Barbato J.E, Zuckerbraun B.S, Overhaus M et al.Nitric oxide modulates vascular inflammation and intimal hyperplasia in insulin resistance and metabolic syndrome. Am J Physiol Heart Circ Physiol 2005; 289: H228–36.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Couillard C, Bergeron N, Prud’homme D et al. Postprandial triglyceride response in visceral obesity in men. Diabetes 1998; 47: 953–60.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Kahn B.B, Flier J.S. Obesity and insulin resistance. J Clin Invest 2000; 106: 473–81.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Mc Farlane S.I, Banerij M, Sowers J.R. Insulin resistance and cardiovascular disease. 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