Consilium MedicumConsilium MedicumConsilium MedicumConsilium Medicum2075-17532542-2170Consilium Medicum92718ArticlesСтатьиResearch ArticleMestnoe lechenie boli: effektivnost' i perenosimost' preparata «Versatis» – plastin s 5% lidokainom dlya nakozhnogo primeneniyaМестное лечение боли: эффективность и переносимость препарата «Версатис» – пластин с 5% лидокаином для накожного примененияAnan'evaL. PАнаньеваЛ. ПГУ Институт ревматологии РАМН15072008107VOL 10, NO7 (2008)ТОМ 10, №7 (2008)10310828122021Copyright ©; 2008, Consilium MedicumCopyright ©; 2008, ООО "Консилиум Медикум"2008Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://consilium.orscience.ru/2075-1753/article/view/92718

В последние годы в клиническую практику с успехом внедряются неинвазивные способы введения лекарственных препаратов через кожу. Внешне напоминающая обычный пластырь, прилипающая к коже полимерная матрица, содержащая лекарственные вещества, обеспечивает постоянную скорость высвобождения активной субстанции и ее стабильное попадание в кожу, где создается тканевое депо-препарата. В зависимости от матричного дизайна, лекарственное средство может диффундировать только в верхние слои кожи или проникать в системный кровоток через сосуды ее нижних слоев.

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