Consilium MedicumConsilium MedicumConsilium MedicumConsilium Medicum2075-17532542-2170Consilium Medicum92908ArticlesСтатьиResearch ArticleKlinicheskaya effektivnost' i bezopasnost' koronarnoy angioplastiki s ispol'zovaniem stentov s lekarstvennym pokrytiem: rezul'taty 5-letnego nablyudeniyaКлиническая эффективность и безопасность коронарной ангиопластики с использованием стентов с лекарственным покрытием: результаты 5-летнего наблюденияAbugovS. AАбуговС. АSaakyanYu. MСаакянЮ. МPolyakovR. SПоляковР. СBilichA. GБиличА. ГГУ РНЦХ им. акад. Б.В.Петровского РАМН, Москва15012009111VOL 11, NO1 (2009)ТОМ 11, №1 (2009)838828122021Copyright ©; 2009, Consilium MedicumCopyright ©; 2009, ООО "Консилиум Медикум"2009Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://consilium.orscience.ru/2075-1753/article/view/92908

Коронарное стентирование (КС) является признанным методом реваскуляризации миокарда, доказав свою высокую клиническую эффективность и безопасность во многих крупных рандомизированных исследованиях. Несмотря на общую тенденцию к расширению показаний, оптимальными кандидатами для проведения КС остаются пациенты с изолированными поражениями коронарных артерий, у которых оптимальная медикаментозная терапия оказалась неэффективной. Малоконтролируемые процессы разрастания неоинтимы, возникающие в стентированном сегменте артерии после коронарной ангиопластики (КА), могут приводить к рецидиву стенокардии, что снижает отдаленную клиническую эффективность КС. Вероятность развития клинически значимого для пациента рестеноза при использовании стентов без лекарственного покрытия колеблется в пределах 15–50% и зависит от морфологических особенностей поражения и сопутствующих заболеваний пациента.

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