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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">93399</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Lechenie sindroma bespokoynykh nog</article-title><trans-title-group xml:lang="ru"><trans-title>Лечение синдрома беспокойных ног</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Levin</surname><given-names>O. S</given-names></name><name xml:lang="ru"><surname>Левин</surname><given-names>О. С</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра неврологии</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Российская медицинская академия последипломного образования</institution></aff></aff-alternatives><aff id="aff2"><institution>Центр экстрапирамидных заболеваний</institution></aff><pub-date date-type="pub" iso-8601-date="2011-02-15" publication-format="electronic"><day>15</day><month>02</month><year>2011</year></pub-date><volume>13</volume><issue>2</issue><issue-title xml:lang="en">VOL 13, NO2 (2011)</issue-title><issue-title xml:lang="ru">ТОМ 13, №2 (2011)</issue-title><fpage>75</fpage><lpage>81</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2011, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2011, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/93399">https://consilium.orscience.ru/2075-1753/article/view/93399</self-uri><abstract xml:lang="ru"><p>Синдром беспокойных ног (СБН) – сенсомоторное расстройство, характеризующееся неприятными ощущениями в нижних конечностях, которые появляются в покое, как правило, в вечернее и ночное время и вынуждают больного совершать облегчающие их движения, что часто приводит к нарушению сна. Современные популяционные исследования показывают, что распространенность СБН среди взрослого населения составляет 2–5%. СБН встречается во всех возрастных группах, но чаще отмечается в среднем и пожилом возрасте (в этой возрастной группе его распространенность достигает 10–35%). Однако не менее 1/3 случаев СБН проявляется на 2–3-м десятилетиях жизни. СБН может быть причиной хронической инсомнии примерно в 15% случаев.СБН относится к частым заболеваниям, но диагностируется редко, в основном из-за малой осведомленности практических врачей, которые зачастую склонны объяснять жалобы больных неврозом, психологическим стрессом, заболеваниями периферических сосудов, суставов, остеохондрозом позвоночника. В большинстве случаев диагностика СБН несложна и основывается преимущественно на жалобах больного.При общем и неврологическом осмотре у больных с первичным СБН обычно не выявляются какие-либо отклонения. Но при вторичном (симптоматическом) СБН можно обнаружить признаки соматического или неврологического заболевания, например, полиневропатии</p></abstract></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Аверьянов Ю.Н., Подчуфарова Е.В. Синдром беспокойных ног. Неврол. журн., 1997; 3: 12–16.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Левин О.С. Синдром беспокойных ног. Экстрапирамидные расстройства. Руководство по диагностике и лечению. Под ред. В.Н.Штока, И.А.Ивановой - Смоленской, О.С.Левина. М.: Медпресс - информ, 2002.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Allen R.P., Picchietti D, Hening W.A. et al. Restless legs syndrome: Diagnostic criteria, special considerations, and epidemiology. A report from the Restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med 2003; 4: 101–19.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Allen R.P.,Walters A.S., Montplaisir J et al. Restless legs syndrome prevalence and impact: REST general population study. Arch Intern Med 2005; 165: 1286–92.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Garcia-Borreguero D. Allen R.P., Kohnen R et al. Diagnostic standards for dopaminergic augmentation of restless legs syndrome: report from a World Association of Sleep Medicine – International Restless Legs Syndrome Study Group consensus conference at the Max Planck Institute. Sleep Med 2007; 8: 520–30.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Hening W,Walters A.S., Allen R.P. et al. Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: The REST (RLS epidemiology, symptoms, and treatment) primary care study. Sleep Med 2004; 5: 237–46.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Hening W.A., Allen R.P., Chokroverty S et al. (eds). Restless legs syndrome. Phyladelphia: Saunders 2009.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Hening W.A., Allen R.P.,Washburn M et al. The four diagnostic criteria for the Restless Legs Syndrome are unable to exclude confounding conditions («mimics»). Sleep Med 2009; 10: 976–81.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Montplaisir J, Godbout R, Poirier G et al. Restless legs syndrome and periodic movements in sleep: physiopathology and treatment with L - DOPA. Clin Neuropharmacol 1986; 9: 456–63.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Montplaisir J, Fantini M.L., Desautels A et al. Long - term treatment with pramipexole in restless legs syndrome. Eur J Neurol 2006; 13: 1306–11.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Oertel W.H., Stiasny-Kolster K, Bergtholdt B et al. Efficacy of pramipexole in restless legs syndrome: A six - week, multicenter, randomized, double - blind study (effect - RLS study). Mov Disord 2007; 22: 213–19.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Oertel W.H., Trenkwalder C, Zucconi M et al. State of the art in restless legs syndrome therapy: practice recommendations for treating restless legs syndrome. Mov Disord 2007; 22 (Suppl l): S. 466–75. P</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>hillips B, Young T, Finn L et al. Epidemiology of restless legs symptoms in adults. Arch Int Med 2000; 160: 2137–41.‌‌</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Quilici S, Abrams K.R., Nicolas A et al. Meta - analysis of the efficacy and tolerability of pramipexole versus ropinirole in the treatment of restless legs syndrome. Sleep Med 2008; 9715–26.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Sloand J.A., Shelly M.A., Feigin A et al. A double - blind, placebocontrolled trial of intravenous iron dextran therapy in patients with ESRD and restless legs syndrome. Am J Kidney Dis 2004; 43: 663–70.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Sommer M, Bachmann C.G., Liebetanz K.M. et al. Pregabalin in restless legs syndrome with and without neuropathic pain. Acta Neurol Scand 2007; 115: 347–50.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>The International Restless Legs Syndrome Study Group. Toward a better definition of the restless legs syndrome. Mov Disord 1995; 10 (5): 634–42.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Trenkwalder C, Henning W.A., Montagna P et al. Treatment of restless legs syndrome: an evidence – based review and implications for clinical practice. Movement Disorders 2008; 23: 2267–302.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Trenkwalder C, Hogl B, Benes H et al. Augmentation in restless legs syndrome is associated with low ferritin. Sleep Med 2008; 9: 572–4.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Wang J, O’Reilly B, Venkataraman R et al. Efficacy of oral iron in patients with restless legs syndrome and a low–normal ferritin: A randomized, double - blind, placebo - controlled study. Sleep Med 2009; 10: 973–5.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Winkelman J.W., Sethi K.D., Kushida C.A., et al. Efficacy and safety of pramipexole in restless legs syndrome. Neurology 2006; 67: 1034–9.</mixed-citation></ref></ref-list></back></article>
