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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">93826</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Gastroezofageal'naya reflyuksnaya bolezn' u beremennykh (lektsiya dlya praktikuyushchikh vrachey)</article-title><trans-title-group xml:lang="ru"><trans-title>Гастроэзофагеальная рефлюксная болезнь у беременных (лекция для практикующих врачей)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sharashkina</surname><given-names>N. V</given-names></name><name xml:lang="ru"><surname>Шарашкина</surname><given-names>Н. В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Runikhina</surname><given-names>N. K</given-names></name><name xml:lang="ru"><surname>Рунихина</surname><given-names>Н. К</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ФГБУ Научный центр акушерства, гинекологии и перинатологии им. акад. В.И.Кулакова Минздрава РФ, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2013</year></pub-date><volume>15</volume><issue>6</issue><issue-title xml:lang="en">VOL 15, NO6 (2013)</issue-title><issue-title xml:lang="ru">ТОМ 15, №6 (2013)</issue-title><fpage>24</fpage><lpage>26</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/93826">https://consilium.orscience.ru/2075-1753/article/view/93826</self-uri><abstract xml:lang="ru"><p>Гастроэзофагеальная рефлюксная болезнь (ГЭРБ) – это хроническое заболевание, протекающее с периодическими обострениями и, как правило, постепенно прогрессирующее. В настоящее время под термином ГЭРБ понимают определенный клинический симптомокомплекс, возникающий в результате заброса содержимого желудка в пищевод вне зависимости от того, возникают ли при этом морфологические изменения дистального отдела пищевода или нет. Выделяют эндоскопически позитивную и эндоскопически негативную ГЭРБ.В основе развития ГЭРБ у беременных лежат те же механизмы, что и вне беременности. Влияние гестации на желудочно-кишечный тракт (ЖКТ) сводится к уменьшению перистальтики кишечника вследствие снижения чувствительности хеморецепторов кишечника к серотонину, гистамину, уменьшению тонуса гладкой мускулатуры кишечника на фоне действия гормонов беременности. Кроме того, имеют место увеличение внутрибрюшного давления и дискоординация активности кишечника, увеличение провоспалительного потенциала мезенхимальных тканей и обострение ранее существовавших воспалительных заболеваний ЖКТ (гастрит, панкреатит, холецистит и др.).</p></abstract></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Шехтман М.М. Руководство по экстрагенитальной патологии у беременных. М., 2008.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Ивашкин В.Т., Шептулин А.А., Трухманов А.С. и др. Рекомендации по обследованию и лечению больных гастроэзофагеальной рефлюксной болезнью. М., 2002.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Dent J, Jones R, Kahrilas P, Talley N.I. Management of gastrooesophageal reflux disease in general practice. BMJ 2001; 322: 344–7.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Gill S.K, O'Brien L, Einarson T.R, Koren G. 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