Consilium MedicumConsilium MedicumConsilium MedicumConsilium Medicum2075-17532542-2170Consilium Medicum94208ArticlesСтатьиResearch ArticleAdenozinovye mekhanizmy polozhitel'nykh i nezhelatel'nykh effektov tikagreloraАденозиновые механизмы положительных и нежелательных эффектов тикагрелораBarbarashO. LБарбарашО. ЛTavluevaE. VТавлуеваЕ. ВФГБУ Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний СО РАМН, Кемерово151020141610VOL 16, NO10 (2014)ТОМ 16, №10 (2014)929428122021Copyright ©; 2014, Consilium MedicumCopyright ©; 2014, ООО "Консилиум Медикум"2014Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://consilium.orscience.ru/2075-1753/article/view/94208

Обзор посвящен механизму действия тикагрелора - антагониста рецепторов P2Y12 тромбоцитов. Обсуждаются положительные и побочные эффекты тикагрелора, связанные с угнетением аденозинового транспортера ENT1, ответственного за подавление внутриклеточного метаболизма аденозина и его накопление.

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