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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">94316</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The main approaches to primary prevention of stroke</article-title><trans-title-group xml:lang="ru"><trans-title>Основные подходы к первичной профилактике мозгового инсульта</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Martsevich</surname><given-names>S. Yu</given-names></name><name xml:lang="ru"><surname>Марцевич</surname><given-names>Сергей Юрьевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф., рук. отд. профилактической фармакотерапии ФГБУ ГНИЦПМ</p></bio><email>smartsevich@gnicpm.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kutishenko</surname><given-names>N. P</given-names></name><name xml:lang="ru"><surname>Кутишенко</surname><given-names>Наталья Петровна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, зав. лаб. фармакоэпидемиологических исследований отд. профилактической фармакотерапии ФГБУ ГНИЦПМ</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Suvorov</surname><given-names>A. Yu</given-names></name><name xml:lang="ru"><surname>Суворов</surname><given-names>Александр Юрьевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>науч. сотр. лаб. фармакоэпидемиологических исследований отд. профилактической фармакотерапии ФГБУ ГНИЦПМ</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">State Research Center for Preventive Medicine of the Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБУ Государственный научно-исследовательский центр профилактической медицины Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-09-15" publication-format="electronic"><day>15</day><month>09</month><year>2015</year></pub-date><volume>17</volume><issue>9</issue><issue-title xml:lang="en">VOL 17, NO9 (2015)</issue-title><issue-title xml:lang="ru">ТОМ 17, №9 (2015)</issue-title><fpage>12</fpage><lpage>15</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/94316">https://consilium.orscience.ru/2075-1753/article/view/94316</self-uri><abstract xml:lang="en"><p>The paper estimated the importance of stroke, are major risk factors for the disease, as well as the estimated basic approaches to its primary drug prevention from the standpoint of evidence-based medicine.</p></abstract><trans-abstract xml:lang="ru"><p>В статье оценивается значимость мозгового инсульта, приводятся основные факторы риска развития заболевания, а также оцениваются основные подходы к его первичной лекарственной профилактике с позиций доказательной медицины.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cerebral stroke</kwd><kwd>risk factors</kwd><kwd>primary drug prevention</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>мозговой инсульт</kwd><kwd>факторы риска</kwd><kwd>первичная медикаментозная профилактика</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Warlow C, Sudlow C, Dennis M et al. 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