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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">94395</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Management of patients with infectious endocarditis at the present stage</article-title><trans-title-group xml:lang="ru"><trans-title>Курация больных инфекционным эндокардитом на современном этапе‌‌‌‌</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Belov</surname><given-names>B. S</given-names></name><name xml:lang="ru"><surname>Белов</surname><given-names>Борис Сергеевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, зав. лаб. изучения роли инфекций при ревматических заболеваниях ФГБНУ НИИ ревматологии им. В.А.Насоновой</p></bio><email>belovbor@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tarasova</surname><given-names>G. M</given-names></name><name xml:lang="ru"><surname>Тарасова</surname><given-names>Галина Михайловна</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, ст. науч. сотр. лаб. изучения роли инфекций при ревматических заболеваниях ФГБНУ НИИ ревматологии им. В.А.Насоновой</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">V.A.Nasonova Research Institute of Rheumatology</institution></aff><aff><institution xml:lang="ru">ФГБНУ Научно-исследовательский институт ревматологии им. В.А.Насоновой</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-01-15" publication-format="electronic"><day>15</day><month>01</month><year>2016</year></pub-date><volume>18</volume><issue>1</issue><issue-title xml:lang="en">VOL 18, NO1 (2016)</issue-title><issue-title xml:lang="ru">ТОМ 18, №1 (2016)</issue-title><fpage>60</fpage><lpage>66</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/94395">https://consilium.orscience.ru/2075-1753/article/view/94395</self-uri><abstract xml:lang="en"><p>The problem of infective endocarditis (IE) continues to maintain its importance because of the high mortality rate and severe complications. Modern IE is a polyetiological disease, the emergence and development of which may be due to pathogens, components of an extremely extensive list, enlarged almost every year. Given the marked clinical polymorphism, special attention is paid to early diagnosis of the disease, including the use of new medical technologies, and the timely use of antimicrobial therapy. In terms of the increasing amount of information of great practical importance is the timely informing of doctors about modern principles of treatment of patients with IE. In the present review, the main approaches to the diagnosis, treatment and prevention of IE taking into account the latest recommendations of experts of the European Society of Cardiology-2015.</p></abstract><trans-abstract xml:lang="ru"><p>Проблема инфекционного эндокардита (ИЭ) по-прежнему сохраняет свою значимость из-за высоких показателей летальности и развития тяжелых осложнений. Современный ИЭ представляет собой полиэтиологичное заболевание, возникновение и развитие которого может быть обусловлено возбудителями, составляющими чрезвычайно обширный перечень, пополняемый практически ежегодно. Учитывая выраженный клинический полиморфизм, особое внимание уделяется ранней диагностике заболевания, в том числе с использованием новых медицинских технологий, а также своевременному назначению эффективной антимикробной терапии. В условиях нарастающего объема информации большое практическое значение имеет своевременное информирование врачей о современных принципах курации больных ИЭ. В настоящем обзоре представлены основные подходы к диагностике, лечению и профилактике ИЭ с учетом последних рекомендаций экспертов Европейского кардиологического общества от 2015 г.</p></trans-abstract><kwd-group xml:lang="en"><kwd>infective endocarditis</kwd><kwd>diagnosis</kwd><kwd>antimicrobial therapy</kwd><kwd>prevention</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>инфекционный эндокардит</kwd><kwd>диагностика</kwd><kwd>антибактериальная терапия</kwd><kwd>профилактика</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Murray C.J, Vos T, Lozano R et al. Disability - adjusted life years (DALYs) for 291 diseases and injures in 21 regions, 1990-2010: a systemic analysis for the Global Burden of Disease Study 2010. 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