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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">94505</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Prospects for treatment of rhinitis and rhinosinusitis: a review of the drug Euphorbium compositum</article-title><trans-title-group xml:lang="ru"><trans-title>Перспективы терапии ринитов и риносинуситов: обзор применения препарата Эуфорбиум композитум</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Marianovskii</surname><given-names>A. A</given-names></name><name xml:lang="ru"><surname>Марьяновский</surname><given-names>Андрей Александрович</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф. каф. госпитальной педиатрии №2 ГБОУ ВПО РНИМУ им. Н.И.Пирогова</p></bio><email>Marjanovsky@arnebia.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО Российский национальный исследовательский медицинский университет им. Н.И.Пирогова Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2016</year></pub-date><volume>18</volume><issue>3</issue><issue-title xml:lang="en">VOL 18, NO3 (2016)</issue-title><issue-title xml:lang="ru">ТОМ 18, №3 (2016)</issue-title><fpage>104</fpage><lpage>106</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/94505">https://consilium.orscience.ru/2075-1753/article/view/94505</self-uri><abstract xml:lang="en"><p>The article presents a review of clinical studies on the efficacy and safety of an intranasal spray Euphorbium compositum. Spray for nasal application is an alternative to conventional drugs used for the treatment of rhinitis and sinusitis, which has no characteristic of these drugs side effects and limitations. The better tolerability compared with xylometazoline can recommend Euphorbium compositum as a means for long-term treatment of chronic sinusitis.The complex mechanism of action of the drug provides its antiviral and anti-inflammatory activity.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлен обзор клинических исследований эффективности и безопасности интраназального спрея Эуфорбиум композитум. Спрей для назального применения представляет собой альтернативу традиционным препаратам, используемым для лечения ринитов и синуситов, не имеющую характерных для этих препаратов побочных эффектов и ограничений. Лучшая переносимость по сравнению с ксилометазолином позволяет рекомендовать Эуфорбиум композитум в качестве средства для длительной терапии хронических синуситов. Комплексный механизм действия препарата обеспечивает его противовирусную и противовоспалительную активность.</p></trans-abstract><kwd-group xml:lang="en"><kwd>rhinitis</kwd><kwd>sinusitis</kwd><kwd>natural ingredients</kwd><kwd>spray</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ринит</kwd><kwd>синусит</kwd><kwd>натуральные компоненты</kwd><kwd>спрей</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Weiser M, Clasen B.P.E. Randomized placebo controlled double - blind study of the clinical efficacy of the homeopathic Euphorbium compositum S-Nasal Spray in cases of chronic sinusitis. Forsch Komplementärmed Klass Naturheilkd 1994; 1: 251-9. English translation in: Biol Therapy 1995; 1: 4-11.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Zenner S, Metelmann H. Therapeutic Experiences with a Homeopathic Nasal Spray. 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