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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">94673</article-id><article-id pub-id-type="doi">10.26442/2075-1753_19.8.2.77-82</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Gallstone disease: correct tactic is the key to successful litholysis</article-title><trans-title-group xml:lang="ru"><trans-title>Желчнокаменная болезнь: правильная тактика - залог успешного литолиза</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vyalov</surname><given-names>S. S</given-names></name><name xml:lang="ru"><surname>Вялов</surname><given-names>Сергей Сергеевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доц. каф. общей практики, врач-гастроэнтеролог, гепатолог GMS clinic &amp; hospitals.</p></bio><email>svialov@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">People’s Friendship University of Russia</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО РУДН, ФГБОУ ВО «МГТУ им. Н.Э.Баумана»</institution></aff></aff-alternatives><aff id="aff2"><institution>N.E.Bauman Moscow State Technical University</institution></aff><aff id="aff3"><institution>Global Medical System clinic &amp; hospitals</institution></aff><pub-date date-type="pub" iso-8601-date="2017-08-19" publication-format="electronic"><day>19</day><month>08</month><year>2017</year></pub-date><volume>19</volume><issue>8-2</issue><issue-title xml:lang="en">NO8-2 (2017)</issue-title><issue-title xml:lang="ru">Том 19, №8-2 (2017)</issue-title><fpage>77</fpage><lpage>82</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/94673">https://consilium.orscience.ru/2075-1753/article/view/94673</self-uri><abstract xml:lang="en"><p>The article deals with data analysis on the tactic of uncomplicated cholelithiasis treatment, taking into account the features of the diagnostic search. Actual studies of methods of cholelithiasis treatment are discussed, including selection of patients - candidates for therapy, using of various drugs of ursodeoxycholic acid, aspects of costs for treatment. It is necessary to fulfill the requirements for diagnosis and selection of patients for oral litholysis, which ensures the success of therapy. Choosing a treatment it is necessary to take into account the characteristics of the drugs, the quality of production and the substance. For illustration, we analyze the clinical case.</p></abstract><trans-abstract xml:lang="ru"><p>В статье приводится анализ данных по тактике лечения неосложненной желчнокаменной болезни с учетом особенностей диагностического поиска. Рассматриваются актуальные исследования методов медикаментозной терапии желчнокаменной болезни, в том числе отбор пациентов - кандидатов на терапию, использование урсодезоксихолевой кислоты, обсуждаются аспекты затрат на лечение. Необходимым представляется выполнение требований к диагностике и подбору пациентов для перорального литолиза, что обеспечивает успех терапии. Следует учитывать особенности препаратов, качество производства и субстанции при выборе средства терапии. В качестве иллюстрации приводится разбор клинического случая.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cholelithiasis</kwd><kwd>biliary sludge</kwd><kwd>biliary dysfunction</kwd><kwd>ursodeoxycholic acid</kwd><kwd>litholysis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>желчнокаменная болезнь</kwd><kwd>билиарный сладж</kwd><kwd>билиарная дисфункция</kwd><kwd>урсодезоксихолевая кислота</kwd><kwd>литолиз</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Heaton K.W, Braddon F.E, Mountford R.A. et al. Symptomatic and silent gall stones in the community. 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