Consilium MedicumConsilium MedicumConsilium MedicumConsilium Medicum2075-17532542-2170Consilium Medicum94791ArticlesСтатьиReview ArticleZika virus: a new factor of intrauterine infectionВирус Зика: новый фактор внутриутробного инфицирования плодаDobrokhotovaYu. EДоброхотоваЮ. Э

д-р мед. наук, проф., зав. каф. акушерства и гинекологии лечебного фак-та ФГБОУ ВО «РНИМУ им. Н.И.Пирогова»

BorovkovaE. IБоровковаЕ. И

д-р мед. наук, проф. каф. акушерства и гинекологии лечебного фак-та ФГБОУ ВО «РНИМУ им. Н.И.Пирогова»

katyanikitina@mail.ruN.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian FederationФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И.Пирогова» Минздрава России15062017196VOL 19, NO6 (2017)ТОМ 19, №6 (2017)576128122021Copyright ©; 2017, Consilium MedicumCopyright ©; 2017, ООО "Консилиум Медикум"2017Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://consilium.orscience.ru/2075-1753/article/view/94791

Infection caused by Zika virus is wide-spread in Africa, South-East Asia and on the Pacific Islands; breakouts are noticed on the American continent. Zika virus is transmissible due to Aedes mosquitoes bites; vertical (diaplacental) and sexually transmitted infection is proved. Clinical implications of Zika virus are developed at 20-25% of patients and include hives, joint pain and conjunctivitis. Zika virus is associated with genuine microcephaly, intracranial calcification, antenatal fetal death and Guillain-Barré syndrome progression. Since mosquito′s bite and before clinical implications occurrence, incubation stage lasts 2-14 days; length of disease is about 7 days. Zika virus infection is diagnosed by means of polymerase chain reaction and blood serological test. To detect intrauterine infection series of ultrasound investigation and diagnostic amniocentesis are carried out. There is no specific treatment for Zika virus infection, as well as preventive vaccine.

Инфекция, вызванная вирусом Зика, распространена в Африке, Юго-Восточной Азии и на островах Тихого океана, выявлены вспышки на американском континенте. Вирус Зика передается трансмиссивно через укус зараженного комара Aedes, доказаны вертикальный (трансплацентарный) и половой пути заражения. Клинические проявления Зика-вирусной инфекции развиваются у 20-25% людей и включают острое начало, субфебрилитет, пятнисто-папулезную сыпь, боль в суставах и конъюнктивит. Вирус Зика ассоциирован с врожденной микроцефалией, внутричерепными кальцификатами, антенатальной гибелью плода и развитием синдрома Гийена-Барре. Инкубационный период между укусом комара и началом клинических проявлений составляет от 2 до 14 дней, средняя продолжительность заболевания - 7 дней. Диагноз Зика-вирусной инфекции устанавливается с помощью полимеразной цепной реакции и серологического исследования крови. Для выявления внутриутробного инфицирования плода проводятся серии ультразвуковых исследований и диагностический амниоцентез. Не существует специфического лечения Зика-вирусной инфекции, и не разработана вакцина для ее профилактики.

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