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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">94792</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">NSAIDs: safety from the point of evidence-based medicine</article-title><trans-title-group xml:lang="ru"><trans-title>Нестероидные противовоспалительные препараты: безопасность с позиции доказательной медицины</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Anikin</surname><given-names>G. S</given-names></name><name xml:lang="ru"><surname>Аникин</surname><given-names>Георгий Станиславович</given-names></name></name-alternatives><email>medi321@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Stozhkova</surname><given-names>I. V</given-names></name><name xml:lang="ru"><surname>Стожкова</surname><given-names>Ирина Владимировна</given-names></name></name-alternatives><bio xml:lang="ru"><p>клин. ординатор 1-го года</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kukes</surname><given-names>V. G</given-names></name><name xml:lang="ru"><surname>Кукес</surname><given-names>Владимир Григорьевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>акад. РАН, д-р мед. наук, проф.</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Первый МГМУ им. И.М.Сеченова»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБОУ ДПО РМАНПО</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-07-19" publication-format="electronic"><day>19</day><month>07</month><year>2017</year></pub-date><volume>19</volume><issue>7-2</issue><issue-title xml:lang="en">VOL 19, NO7-2 (2017)</issue-title><issue-title xml:lang="ru">ТОМ 19, №7-2 (2017)</issue-title><fpage>28</fpage><lpage>32</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/94792">https://consilium.orscience.ru/2075-1753/article/view/94792</self-uri><abstract xml:lang="en"><p>Prescribing of NSAIDs in modern clinical practice is a routine procedure. However, all aspects of NSAIDs safety are often not assessed. The article highlights the main aspects of safe prescription of NSAIDs, which every doctor should be guided in his practice.</p></abstract><trans-abstract xml:lang="ru"><p>Назначение нестероидных противовоспалительных препаратов (НПВП) в современной клинической практике - рутинная процедура. Однако зачастую не оцениваются все аспекты безопасности приема НПВП. В статье освещены основные аспекты безопасности приема НПВП, которыми должен руководствоваться врач в своей практике.</p></trans-abstract><kwd-group xml:lang="en"><kwd>nonsteroidal anti-inflammatory drugs</kwd><kwd>anesthesia</kwd><kwd>safety profile</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>нестероидные противовоспалительные препараты</kwd><kwd>обезболивание</kwd><kwd>профиль безопасности</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Starling A.J, Hoffman-Snyder C. 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