Consilium MedicumConsilium MedicumConsilium MedicumConsilium Medicum2075-17532542-2170Consilium Medicum94802ArticlesСтатьиResearch ArticleModern possibilities of correcting iron deficiency anemia in patients with pathology of the digestive systemСовременные возможности коррекции железодефицитной анемии у пациентов с патологией пищеварительной системыKudykinM. NКудыкинМаксим Николаевич

д-р мед. наук, проф., вед. науч. сотр., вице-президент Ассоциации флебологов России

mady5@yandex.ruVolga Region Federal Medical Research Center of the Ministry of Health of the Russian FederationФГБУ ПФМИЦ19072017197-2VOL 19, NO7-2 (2017)ТОМ 19, №7-2 (2017)364128122021Copyright ©; 2017, Consilium MedicumCopyright ©; 2017, ООО "Консилиум Медикум"2017Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://consilium.orscience.ru/2075-1753/article/view/94802

Iron deficiency anemia (IDA) is associated with several pathologic conditions of the gastrointestinal tract. In addition to inflammatory bowel disease, IDA is often associated with chronic liver disease. Different factors such as chronic blood loss, malabsorption, inflammation, may contribute to the development of IDA. Although patients with symptoms of anemia often initially turn to gastroenterologists approach to diagnosis and treatment, as well as measures for subsequent monitoring of the patient are not standardized and optimal. Iron deficiency, even without the development of symptoms of anemia, can significantly affect the physical health and cognitive function, reduce quality of life. So important is regular assessment of iron concentration and understanding of the clinical consequences of reducing the concentration of serum iron by specialists of different profile: surgeons, internists, cardiologists. Currently, the range of treatment options awaiting increases due to the introduction into clinical practice of effective and well-tolerated iron preparations for parenteral administration. Available in scientific periodicals there is a lack of systematic reviews for the treatment of IDA and, in particular, its treatment for patients with diseases of the gastrointestinal tract. In the presented review summarizes the current understanding of the period of awaiting for specific gastrointestinal and hepatic disorders and discusses a unified approach to the treatment of anemia and iron deficiency in daily clinical practice.

Железодефицитная анемия (ЖДА) связана с рядом патологических состояний желудочно-кишечного тракта. Помимо воспалительных заболеваний кишечника ЖДА часто ассоциирована с хроническими заболеваниями печени. Разные факторы, такие как хроническая кровопотеря, мальабсорбция, воспаление, могут способствовать развитию ЖДА. Хотя пациенты с симптомами анемии часто первично обращаются за помощью к гастроэнтерологам, подход к диагностике и лечению, а также меры по последующему контролю за пациентом не являются стандартизированными и оптимальными. Дефицит железа, даже без развития симптомов анемии, может существенно повлиять на состояние физического здоровья и когнитивную функцию, снизить качество жизни. Поэтому важны регулярная оценка концентрации железа и понимание клинических последствий снижения концентрации сывороточного железа также со стороны специалистов другого профиля: хирургов, терапевтов, кардиологов. В настоящее время диапазон вариантов лечения ЖДА увеличивается за счет внедрения в клиническую практику эффективных и хорошо переносимых препаратов железа для парентерального введения. В доступной научной периодике отмечается недостаток систематических обзоров, касающихся лечения ЖДА и, в частности, ее терапии у пациентов с заболеваниями желудочно-кишечного тракта. В представленном обзоре обобщается современное представление о течении ЖДА при специфических желудочно-кишечных и печеночных расстройствах и рассматривается унифицированный подход к лечению анемии и дефицита железа в повседневной клинической практике.

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