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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">94923</article-id><article-id pub-id-type="doi">10.26442/2075-1753_19.10.85-88</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Statins and the liver: a point of view from the cardiologist</article-title><trans-title-group xml:lang="ru"><trans-title>Статины и печень: взгляд кардиолога</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ostroumova</surname><given-names>O. D</given-names></name><name xml:lang="ru"><surname>Остроумова</surname><given-names>Ольга Дмитриевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф. каф. факультетской терапии и профболезней; проф. каф. клинической фармакологии и пропедевтики внутренних болезней</p></bio><email>ostroumova.olga@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И.Евдокимова» Минздрава России</institution></aff></aff-alternatives><aff id="aff2"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М.Сеченова» Минздрава России</institution></aff><pub-date date-type="pub" iso-8601-date="2017-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2017</year></pub-date><volume>19</volume><issue>10</issue><issue-title xml:lang="en">VOL 19, NO10 (2017)</issue-title><issue-title xml:lang="ru">ТОМ 19, №10 (2017)</issue-title><fpage>85</fpage><lpage>88</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/94923">https://consilium.orscience.ru/2075-1753/article/view/94923</self-uri><abstract xml:lang="en"><p>The article is devoted to the safety of statins in terms of hepatotoxicity. These recommendations are presented in terms of monitoring liver function in patients receiving statins. The choice of the optimal scheme of statin therapy from the perspective of the efficiency/safety ratio are discussed.</p></abstract><trans-abstract xml:lang="ru"><p>Статья посвящена безопасности статинов с точки зрения гепатотоксичности. Представлены данные рекомендаций в плане мониторирования функции печени у пациентов, получающих статины. Обсуждаются вопросы выбора оптимальной схемы лечения статинами с позиции соотношения эффективность/безопасность.</p></trans-abstract><kwd-group xml:lang="en"><kwd>statin</kwd><kwd>HMGCoA reductase inhibitor</kwd><kwd>rosuvastatin</kwd><kwd>efficacy</kwd><kwd>safety</kwd><kwd>adverse effects</kwd><kwd>hepatotoxicity</kwd><kwd>pharmacokinetics</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>статины</kwd><kwd>ингибиторы редуктазы гидроксиметил-глютарового кофермента А</kwd><kwd>розувастатин</kwd><kwd>эффективность</kwd><kwd>безопасность</kwd><kwd>побочные эффекты</kwd><kwd>гепатотоксичность</kwd><kwd>фармакокинетика</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Catapano A.L, Graham I, De Backer G et al. 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias. 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