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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">95105</article-id><article-id pub-id-type="doi">10.26442/20751753.2018.12.000052</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Symptomatic pharmacotherapy of stable ischemic heart disease: principles of adjustment</article-title><trans-title-group xml:lang="ru"><trans-title>Симптоматическая фармакотерапия стабильной ишемической болезни сердца: принципы точной настройки</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Perepech</surname><given-names>N. B</given-names></name><name xml:lang="ru"><surname>Перепеч</surname><given-names>Никита Борисович</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф., рук. научно-клинического и образовательного центра «Кардиология» Института высоких медицинских технологий</p></bio><email>nikita_perepech@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Saint Petersburg State University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Санкт-Петербургский государственный университет»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2018</year></pub-date><volume>20</volume><issue>12</issue><issue-title xml:lang="en">VOL 20, NO12 (2018)</issue-title><issue-title xml:lang="ru">ТОМ 20, №12 (2018)</issue-title><fpage>8</fpage><lpage>14</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/95105">https://consilium.orscience.ru/2075-1753/article/view/95105</self-uri><abstract xml:lang="en"><p>The article discusses the existing guidelines on stable ischemic heart disease pharmacotherapy. The main principles of approach to personalization of stable angina symptomatic therapy with rationale for antianginal medications choice depending on clinical and pathophysiological phenotypes of the patient are discussed. Aspects of combined therapy for stable angina and use of antianginal medications fixed combinations are presented</p></abstract><trans-abstract xml:lang="ru"><p>В статье обсуждаются действующие рекомендации по фармакотерапии стабильной ишемической болезни сердца. Приводятся основные положения «бриллиантового» подхода к персонализации симптоматической терапии стабильной стенокардии с обоснованием выбора антиангинальных лекарственных средств в зависимости от клинического и патофизиологического фенотипов больного. Рассматриваются аспекты комбинированной терапии стабильной стенокардии и фиксированные комбинации антиангинальных лекарственных препаратов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>stable angina</kwd><kwd>antianginal medications</kwd><kwd>fixed combinations</kwd><kwd>pharmacotherapy personalization</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>стабильная стенокардия</kwd><kwd>антиангинальные препараты</kwd><kwd>фиксированные комбинации</kwd><kwd>персонализация фармакотерапии</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Boden W.E, O'Rourke R.A, Teo K.K et al. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med 2007; 356 (15): 1503-16.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Al-Lamee R, Thompson D, Dehbi H.M et al. Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial. 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