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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">95298</article-id><article-id pub-id-type="doi">10.26442/20751753.2020.10.200291</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Miscellaneous</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Clinical case of successful use of non-invasive ventilation in a patient with a new coronavirus infection</article-title><trans-title-group xml:lang="ru"><trans-title>Клинический случай успешного применения неинвазивной вентиляции легких у пациента с новой коронавирусной инфекцией</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Litvin</surname><given-names>Aleksandr Yu.</given-names></name><name xml:lang="ru"><surname>Литвин</surname><given-names>Александр Юрьевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, рук. лаб. апноэ сна, гл. науч. сотр. отд. гипертонии</p></bio><email>alelitvin@yandex.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Elfimova</surname><given-names>Evgeniia M.</given-names></name><name xml:lang="ru"><surname>Елфимова</surname><given-names>Евгения Михайловна</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, науч. сотр. лаб. апноэ сна отд. гипертонии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mikhailova</surname><given-names>Oksana O.</given-names></name><name xml:lang="ru"><surname>Михайлова</surname><given-names>Оксана Олеговна</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, мл. науч. сотр. лаб. апноэ сна отд. гипертонии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Alekseeva</surname><given-names>Tatiana A.</given-names></name><name xml:lang="ru"><surname>Алексеева</surname><given-names>Татьяна Анатольевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, врач-кардиолог 5-го кардиологического отделения гипертонии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sivakova</surname><given-names>Olga A.</given-names></name><name xml:lang="ru"><surname>Сивакова</surname><given-names>Ольга Анатольевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, зав. 5-м кардиологическим отд-нием</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Danilov</surname><given-names>Nikolai M.</given-names></name><name xml:lang="ru"><surname>Данилов</surname><given-names>Николай Михайлович</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, вед. науч. сотр. отд. гипертонии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pevzner</surname><given-names>Dmitrii V.</given-names></name><name xml:lang="ru"><surname>Певзнер</surname><given-names>Дмитрий Вольфович</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, зав. блоком интенсивной терапии отд. неотложной кардиологии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Dulaev</surname><given-names>Lavrentii O.</given-names></name><name xml:lang="ru"><surname>Дулаев</surname><given-names>Лаврентий Олегович</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-кардиолог блока интенсивной терапии отд. неотложной кардиологии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zyuryaev</surname><given-names>Ilia T.</given-names></name><name xml:lang="ru"><surname>Зюряев</surname><given-names>Илья Тарасович</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач анестезиолог-реаниматолог блока интенсивной терапии отд. неотложной кардиологии</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gaman</surname><given-names>Svetlana A.</given-names></name><name xml:lang="ru"><surname>Гаман</surname><given-names>Светлана Анатольевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, науч. сотр. лаб. РКТ отд. томографии</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Medical Research Center for Cardiology</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр кардиологии» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Pirogov Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2020</year></pub-date><volume>22</volume><issue>10</issue><issue-title xml:lang="en">VOL 22, NO10 (2020)</issue-title><issue-title xml:lang="ru">ТОМ 22, №10 (2020)</issue-title><fpage>23</fpage><lpage>28</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/95298">https://consilium.orscience.ru/2075-1753/article/view/95298</self-uri><abstract xml:lang="en"><p>The new coronavirus disease COVID-19 (SARS-CoV-2) is a challenge both in terms of optimal patient management and the protection of the medical personnel. We present a clinical case of a 49-year-old patient with bilateral polysegmental pneumonia (COVID-19), complicated by acute respiratory distress syndrome and a cytokine storm, in whom the chosen treatment tactics using non-invasive ventilation allowed avoidance of intubation together with organization of sufficient protection for medical personnel.</p></abstract><trans-abstract xml:lang="ru"><p>Новая коронавирусная инфекция COVID-19 (SARS-CoV-2) - это вызов как с точки зрения оптимальной тактики ведения больных, так и защиты медицинского персонала. Мы приводим клинический случай пациента 49 лет с двусторонней полисегментарной пневмонией (COVID-19), осложнившейся острым респираторным дистресс-синдромом и «цитокиновым штормом», у которого выбранная тактика терапии с использованием неинвазивной вентиляции легких позволила избежать интубации и организовать адекватную защиту медицинского персонала.</p></trans-abstract><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>non-invasive ventilation</kwd><kwd>COVID-19</kwd><kwd>new coronavirus infection</kwd><kwd>pneumonia</kwd><kwd>respiratory support</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>неинвазивная вентиляция легких</kwd><kwd>новая коронавирусная инфекция</kwd><kwd>пневмония</kwd><kwd>респираторная поддержка</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Guan W, Ni Z, Hu Y et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med 2020; 382: 1708-20. DOI: 10.1056/NEJMoa2002032</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Wang D, Hu B, Hu C et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA 2020. DOI: 10.1001/jama.2020.1585</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Hernandez AV, Roman YM, Pasupuleti V et al. Hydroxychloroquine or Chloroquine for Treatment or Prophylaxis of COVID-19: A Living Systematic Review. Ann Intern Med 2020; 10.7326/M20-2496. DOI: 10.7326/M20-2496</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Cao B, Wang Y, Wen D et al. A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19. N Engl J Med 2020; 382 (19): 1787-99. DOI: 10.1056/NEJMoa2001282</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Alattar R, Ibrahim TBH, Shaar SH et al. Tocilizumab for the treatment of severe COVID-19. J Med Virol 2020; 1-8. DOI: 10.1002/jmv.25964</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Michot JM, Albiges L, Chaput N et al. Tocilizumab, an anti-IL6 receptor antibody, to treat Covid-19-related respiratory failure: a case report. Ann Oncol 2020. DOI: 10.1016/j.annonc.2020.03.300.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Lillicrap D. Disseminated intravascular coagulation in patients with 2019-nCoV pneumonia. J Thromb Haemost 2020. DOI: 10.1111/jth.14781</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Zhang Y, Xiao M, Zhang S et al. Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19. N Engl J Med 2020. DOI: 10.1056/NEJMc2007575</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Huang C, Wang Y, Li X et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395: 497-506. DOI: 10.1016/S0140-6736(20)30183-5</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Brochard L, Slutsky A, Pesenti A. Mechanical ventilation to minimize progression of lung injury in acute respiratory failure. Am J Respir Crit Care Med 2017; 195 (4): 438-42. DOI: 10.1164/rccm.201605-1081CP</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Marini JJ, Gattinoni L. Management of COVID-19 Respiratory Distress. JAMA 2020. DOI: 10.1001/jama.2020.6825</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Nicolini A, Cilloniz C, Piroddi IG et al. Noninvasive ventilation for acute respiratory failure due to community-acquired pneumonia: A concise review and update. Community Acquired Infection 2015; 2 (2): 46. DOI: 10.4103/2225-6482.159224</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Yang X, Yu Y, Xu J et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med 2020. DOI: 10.1016/S2213-2600(20)30079-5</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Tran K, Cimon K, Severn M et al. Aerosol generating procedures and risk of transmission of acute respiratory infections to healthcare workers: a systematic review. PLoS One 2012; 7: e35797. DOI: 10.1371/journal.pone.0035797. PMID: 22563403.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Hui DS, Chow BK, Lo T et al. Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks. Eur Respir J 2019; 53 (4): 1802339. DOI: 10.1183/13993003.02339-2018</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Simonds AK, Hanak A, Chatwin M et al. Evaluation of droplet dispersion during non-invasive ventilation, oxygen therapy, nebuliser treatment and chest physiotherapy in clinical practice: implications for management of pandemic influenza and other airborne infections. Health Technol Assess 2010; 14 (46): 131-72. DOI: 10.3310/hta14460-02</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Nicas M, Nazaroff WW, Hubbard A. Toward understanding the risk of secondary airborne infection: emission of respirable pathogens. J Occup Environ Hyg 2005; 2 (3): 143-54. DOI: 10.1080/15459620590918466</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Bourouiba L. Turbulent Gas Clouds and Respiratory Pathogen Emissions: Potential Implications for Reducing Transmission of COVID-19. JAMA 2020; 10.1001/jama.2020.4756. DOI: 10.1001/jama.2020.4756. PMID: 32215590</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>NHS (2020). Guidance for the role and use of non-invasive respiratory support in adult patients with coronavirus (confirmed or suspected). 2020 March 26.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Seto WH, Tsang D, Yung RW et al. Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS). Lancet 2003; 361: 1519-20. DOI: 10.1016/s0140-6736(03)13168-6</mixed-citation></ref></ref-list></back></article>
