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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">95320</article-id><article-id pub-id-type="doi">10.26442/20751753.2020.8.200026</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Miscellaneous</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Leser-Trelat sign in patients with colon cancer: clinical case</article-title><trans-title-group xml:lang="ru"><trans-title>Синдром Лезера-Трела при раке ободочной кишки: собственное наблюдение</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Balutsky</surname><given-names>Viktor V.</given-names></name><name xml:lang="ru"><surname>Балуцкий</surname><given-names>Виктор Викторович</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, зав. гастроэнтерологическим отд-нием</p></bio><email>viktor-baluckij@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vinogradov</surname><given-names>Ilya A.</given-names></name><name xml:lang="ru"><surname>Виноградов</surname><given-names>Илья Анатольевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, врач колопроктологического отд-ния</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Federal 1586 Military Clinical Hospital</institution></aff><aff><institution xml:lang="ru">ФГКУ «1586 Военный клинический госпиталь» Минобороны России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-08-15" publication-format="electronic"><day>15</day><month>08</month><year>2020</year></pub-date><volume>22</volume><issue>8</issue><issue-title xml:lang="en">VOL 22, NO8 (2020)</issue-title><issue-title xml:lang="ru">ТОМ 22, №8 (2020)</issue-title><fpage>90</fpage><lpage>92</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/95320">https://consilium.orscience.ru/2075-1753/article/view/95320</self-uri><abstract xml:lang="en"><p>Leser-Trelat sign that manifests as eruption of multiple seborrheic keratoses is a rare but valuable for diagnostics paraneoplastic syndrome. We present a clinical case of Leser-Trelat sign in a patient with colon cancer. Our opinion s that all patients with sudden onset and rapid progression of seborrheic keratoses should be included in diagnostic screening for undetected malignant process.</p></abstract><trans-abstract xml:lang="ru"><p>Синдром Лезера-Трела, манифестирующий как эруптивный множественный себорейный кератоз, является редким, но диагностически ценным па-ранеопластическим синдромом. Представлено клиническое наблюдение синдрома Лезера-Трела у пациента с раком ободочной кишки. Мы считаем, что все пациенты с внезапным появлением и быстрым прогрессированием себорейных кератом должны подвергаться диагностическому скринингу на предмет скрытого онкологического заболевания.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Leser-Trelat sign</kwd><kwd>colon cancer</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>синдром Лезера-Трела</kwd><kwd>рак ободочной кишки</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Хидченко С.В., Апанасович В.Г., Чиж К.А. Паранеопластические синдромы. Учебно-методическое пособие. Минск: БГМУ, 2018.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Русак Ю.Э., Ефанова Е.Н., Павлова Е.В. и др. Синдром Лезера-Трела у больной меланомой. Клин.дерматология и венерология. 2017; 4: 26-30.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Олисова О.Ю., Теплюк Н.П., Грабовская О.В. и др. Кератодермии как паранеопластический синдром. 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