Consilium MedicumConsilium MedicumConsilium MedicumConsilium Medicum2075-17532542-2170Consilium Medicum9536310.26442/20751753.2020.12.200309ArticlesСтатьиReview ArticleProand synbiotics in the treatment of intestinal diseases: what effects can we expect?Про- и синбиотики в лечении заболеваний кишечника: на какие эффекты мы можем рассчитывать?GausOlga V.ГаусОльга Владимировна

канд. мед. наук, ассистент каф. факультетской терапии

gaus_olga@bk.ruLivzanMaria A.ЛивзанМария Анатольевна

д-р мед. наук, проф., зав. каф. факультетской терапии

Omsk State Medical UniversityФГБОУ ВО «Омский государственный медицинский университет» Минздрава России151220202212VOL 22, NO12 (2020)ТОМ 22, №12 (2020)374328122021Copyright ©; 2020, Consilium MedicumCopyright ©; 2020, ООО "Консилиум Медикум"2020Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://consilium.orscience.ru/2075-1753/article/view/95363

The relationship between intestinal microbiota and human health is widely recognized. The advent of molecular and genetic diagnostic methods has made it possible to make truly revolutionary discoveries in the field of understanding the role of the digestive tract microbiome. Many studies have proved the association of the composition of microbiota with the development of a number of diseases of the digestive tract, such as inflammatory bowel diseases, functional gastrointestinal disorders and some types of cancer. The food and pharmaceutical industry has presented a huge selection of food products, dietary supplements and medicines containing prebiotic and probiotic components. The use of agents that affect microbiota in the treatment of intestinal diseases in real clinical practice should be carried out strictly in accordance with the indications, in recommended doses.

Связь между кишечной микробиотой и состоянием здоровья человека является общепризнанной. Появление молекулярных и генетических методов диагностики позволило сделать поистине революционные открытия в области понимания роли микробиома пищеварительного тракта. Во многих исследованиях доказана ассоциация измененного под воздействием факторов окружающей среды состава микробиоты с развитием целого ряда заболеваний пищеварительного тракта, таких как воспалительные заболевания кишечника, функциональные гастроинтестинальные расстройства, некоторые виды рака. Одновременно с этим пищевая и фармацевтическая промышленность представила огромный выбор продуктов питания, биологически активных добавок и лекарственных средств, содержащих пребиотические и пробиотические компоненты. Несмотря на растущее число исследований по эффективности средств, влияющих на микробиоту, их применение в реальной клинической практике должно осуществляться строго в соответствии с показаниями, в рекомендованных дозах.

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