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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Consilium Medicum</journal-id><journal-title-group><journal-title xml:lang="en">Consilium Medicum</journal-title><trans-title-group xml:lang="ru"><trans-title>Consilium Medicum</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Consilium Medicum</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2075-1753</issn><issn publication-format="electronic">2542-2170</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">95375</article-id><article-id pub-id-type="doi">10.26442/20751753.2020.11.200369</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Changes in markers of hematological, biochemical and coagulological blood tests with coronavirus COVID-19 infections</article-title><trans-title-group xml:lang="ru"><trans-title>Изменения маркеров гематологического, биохимического и коагулологического анализов крови при новой коронавирусной инфекции COVID-19</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Abdullaev</surname><given-names>Rizvan Yu.</given-names></name><name xml:lang="ru"><surname>Абдуллаев</surname><given-names>Ризван Юсиф Оглы</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф., вед. науч. сотр. отд. патанатомии, электронной микроскопии и биохимии, зав. лаб. биохимии</p></bio><email>rizvan0403@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Komissarova</surname><given-names>Oksana G.</given-names></name><name xml:lang="ru"><surname>Комиссарова</surname><given-names>Оксана Геннадьевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, зам. дир. по научной и лечебной работе ФГБНУ ЦНИИТ, проф. каф. фтизиатрии лечебного фак-та</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Central Research Institute of Tuberculosis</institution></aff><aff><institution xml:lang="ru">ФГБНУ «Центральный научно-исследовательский институт туберкулеза»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Pirogov Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-11-15" publication-format="electronic"><day>15</day><month>11</month><year>2020</year></pub-date><volume>22</volume><issue>11</issue><issue-title xml:lang="en">VOL 22, NO11 (2020)</issue-title><issue-title xml:lang="ru">ТОМ 22, №11 (2020)</issue-title><fpage>51</fpage><lpage>55</lpage><history><date date-type="received" iso-8601-date="2021-12-28"><day>28</day><month>12</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://consilium.orscience.ru/2075-1753/article/view/95375">https://consilium.orscience.ru/2075-1753/article/view/95375</self-uri><abstract xml:lang="en"><p>This review provides new literature data on the features of changes in the indicators of clinical and biochemical analysis of blood, as well as hemostatic and fibrinolysis systems in patients with coronavirus infection COVID-19. It was shown that laboratory manifestations of COVID-19 have their own characteristics and are closely interrelated with the nature of the course of infection. In a clinical blood test, lymphopenia and thrombocytopenia are most common. Among the biochemical parameters of blood, an increase in the level of C-reactive protein and ferritin, as well as a decrease in the level of albumin, are more often detected. It should be noted that in 1/3 of severe patients with COVID-19 infection, the activity of liver enzymes, ALT and AST, increases. Among the indicators of hemostasis and fibrinolysis systems, an increase in the concentration of D-dimer in blood plasma is more often detected. The review also analyzes the possible causes of changes in some laboratory parameters with COVID-19.</p></abstract><trans-abstract xml:lang="ru"><p>В обзоре приводятся новые литературные данные об особенностях изменений показателей клинического и биохимического анализов крови, а также систем гемостаза и фибринолиза у больных с коронавирусной инфекцией COVID-19. Показано, что лабораторные проявления COVID-19 имеют свои особенности и тесно взаимосвязаны с характером течения инфекции. В клиническом анализе крови наиболее часто встречаются лимфопения и тромбоцитопения. Среди биохимических показателей крови чаще выявляются повышение уровня С-реактивного белка и ферритина, а также снижение уровня альбумина. Следует отметить, что у 1/3 тяжелых больных с инфекцией COVID-19 нарастает активность печеночных ферментов - аланинаминотрансферазы и аспартатаминотрансферазы. Среди показателей систем гемостаза и фибринолиза чаще выявляется повышение концентрации Д-димера в плазме крови. В обзоре также анализируются возможные причины изменений некоторых лабораторных показателей при COVID-19.</p></trans-abstract><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>COVID-19</kwd><kwd>lymphopenia</kwd><kwd>thrombocytopenia</kwd><kwd>C-reactive protein</kwd><kwd>procalcitonin</kwd><kwd>ferritin</kwd><kwd>D-dimer</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>лимфопения</kwd><kwd>тромбоцитопения</kwd><kwd>С-реактивный белок</kwd><kwd>прокальцитонин</kwd><kwd>ферритин</kwd><kwd>Д-димер</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Guan WJ, Ni ZY, Hu Y et al. China Medical Treatment Expert Group for COVID-19. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020. DOI: 10.1056/NEJMoa2002032</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Wang D, Hu B, Hu C et al. 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