Consilium MedicumConsilium MedicumConsilium MedicumConsilium Medicum2075-17532542-2170Consilium Medicum9542810.26442/20751753.2021.2.200727ArticlesСтатьиReview ArticleClinical pharmacological particular qualities of original ibuprofen different forms in treatment of diseases manifesting by painКлинико-фармакологические особенности различных форм оригинального ибупрофена при лечении заболеваний, проявляющихся больюPchelintsevMikhail V.ПчелинцевМихаил Владимирович

канд. мед. наук, доц. каф.

mvpchelintsev@inbox.ruPavlov First Saint Petersburg State Medical UniversityФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова» Минздрава России15022021232VOL 23, NO2 (2021)ТОМ 23, №2 (2021)17518028122021Copyright ©; 2021, Consilium MedicumCopyright ©; 2021, ООО "Консилиум Медикум"2021Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://consilium.orscience.ru/2075-1753/article/view/95428

In the present article, the role of non-steroidal anti-inflammatory drugs in treatment of different diseases manifesting by nociceptive pain is viewed. Special consideration is given to Ibuprofen, which is very often used as a non-prescription analgesic and/or anti-pyretic agent. Using the examples of randomized clinical trials and meta-analyzes carried on their basis, a high comparative analgesic efficacy and safety of use of original ibuprofen, Nurofen®, in different pharmaceutical forms in particular in a form of rapidly absorbed tablets and in combination with paracetamol.

В публикации рассматривается роль нестероидных противовоспалительных препаратов в лечении различных заболеваний, проявляющихся ноцицептивной болью. Особое внимание уделено ибупрофену, который очень часто используется в качестве безрецептурного анальгетика и/или антипиретика. На примерах результатов рандомизированных клинических исследований и выполненных на их основе метаанализов подчеркиваются высокий уровень анальгезии и безопасность при применении различных лекарственных форм оригинального ибупрофена, Нурофена, в частности в форме быстро всасывающихся таблеток и в комбинации с парацетамолом.

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