Consilium Medicum
Peer-review medical journal
Editor-in-chief
- Prof. Victor V. Fomin, MD, Dr. Sci. (Medicine)
ORCID ID: https://orcid.org/0000-0002-2682-4417
Publisher
- CONSILIUM MEDICUM LLC
WEB: https://omnidoctor.ru/
About
Professional medical multidisciplinary journal , based on the principles of evidence-based medicine. Consilium Medicum magazine has been issued since 1999.
The journal publishes national and international recommendations, reviews, lectures, original works, and clinical cases dealing with the most actual problems of the modern medicine, as well as interviews with experts within the different fields of medicine and conferences, congresses and forums reviews.
The journal is practically-oriented and publishes articles by leading clinicians who are professional in the special field of medicine in Russia, Ukraine, Belarus, and includes the high level of scientific information.
Consilium Medicum journal is the most popular journal among medical practitioners. There are 12 thematic issues per year. The journal is designed for therapeutists, pediatricians, cardiologists, endocrinologists, gastroenterologists, pulmonologists, dermatologists, obstetrician-gynecologists, urologists, nephrologists, neurologists, rheumatologists and physicians in other specialties, as well as for resident physicians, post-graduate students and senior students at medical universities.
Types of accepted articles
- reviews, systematic reviews and meta-analysis
- original research
- clinical case reports and series of clinical cases
- letters to the editor
- hystorical articles in medicine
Research fields
- Internal medicine
- Endocrinology
- Otorhinolaryngology
- Cardiology
- Neurology
- Phthisiology
- Surgery
- Rheumatology
- Urology
- Pulmonology
- Gastroenterology
- Gerontology and geriatrics
Publication, distribution and indexation
- Russian and English full-text articles;
- issues publish monthly, 12 times per year;
- no APC, Platinum Open Access
- articles distributr under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (CC BY-NC-SA 4.0).
Indexation
- Russian Science Citation Index (elibrary.ru)
- DOAJ
- CrossRef
- Google Scholar
- WorldCat
- Ulrich's Periodicals Directory
- CyberLeninka
Current Issue
Vol 26, No 5 (2024): Гастроэнтерология
Articles
Modern methods of diagnosis and treatment of inflammatory bowel diseases
Abstract
The treatment of patients with inflammatory bowel disease is an ever-evolving field of medicine. However, doctors often face difficulties in managing such patients. In this interview, E.A. Belousova shares her expert opinion on modern methods of diagnosis and treatment of inflammatory bowel disease, paying special attention to a multidisciplinary approach to the management of concomitant diseases and the prevention of complications caused by drug therapy.
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Stress and its impact on the mucosal membranes of the digestive tract: morphological and functional alterations. A review
Abstract
Studies of morphological changes in the mucous membranes of the digestive tract under stress are highly relevant in medical science and practice. Understanding these changes can be key to developing effective prevention and treatment methods for related problems. It is also important to improve the quality of life of people who are stressed in various areas of life. The literature review examines the physiological changes in the digestive tract under stress. Stress causes a complex effect on the functional state of the digestive system, including changes in blood supply, peristalsis and enzyme production. Such processes can lead to digestive disorders and aggravation of disorders.
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Medical аnd еconomic аspects оf the use of vacuum therapy for esophageal injures
Abstract
Background. Currently, endoscopic vacuum therapy (EVT) with an efficiency of up to 90% or more is actively used in the treatment of esophageal injuries. At the same time, the economic assessment of the advantages of minimally invasive methods has not been studied enough.
Aim. To Analysis of the economic component of EVT for esophageal injuries in comparison with classical interventions (thoracotomy, esophageal extirpation) in a regional multidisciplinary hospital.
Materials and methods. The analysis of the economic component of EVT in comparison with classical interventions was carried out by retrospectively examining the medical records of 43 patients. The cost of treatment in the comparison groups was estimated by including the cost of the patient's stay in the hospital and the direct costs of intervention.
Results. The conducted statistical analysis showed significant differences in the groups with a strong dependence of the cost of treatment on the patient's stay in the intensive care units and the direct costs of open surgery.
Conclusion. The use of minimally invasive and modern EVT methods for esophageal injuries can significantly shorten the patient's hospital stay. Compared to traditional surgical approaches, this approach allows for a reduction in the financial aspect by more than two times.
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Analysis of clinical manifestations, course and results of treatment of acute pancreatitis in patients of an emergency surgical hospital
Abstract
Background. Over the past 10–15 years, there has been a clear trend towards improving the diagnosis and treatment of acute pancreatitis. However, even at the current stage of technology development, a number of difficulties arise in making an accurate diagnosis, in determining the volume and timing of surgical intervention, in organizing measures to prevent complications, treatment and further recovery of patients after acute pancreatitis.
Aim. To analyze the structure of morbidity and treatment outcomes of patients with acute pancreatitis in an emergency surgical hospital.
Materials and methods. We analyzed the structure of pathology and incidence of acute pancreatitis in patients of the 5th and 6th surgical departments. The sample consisted of 2033 patients diagnosed with acute pancreatitis. Of these, 973 people are patients of the 5th surgical department, 1060 people are patients of the 6th surgical department. The work used standard mathematical and statistical methods of data processing.
Results. The results indicate that in the structure of surgical pathology, the predominant diagnoses are acute pancreatitis, unspecified, and other acute pancreatitis. At the same time, these are also those forms of the disease that are characterized by high mortality. On average, 1 patient takes 9–10 bed days, which indicates the high medical and social significance of these forms of pathology. All the data obtained confirm the fact that many patients require emergency surgical care, even at a stage when the diagnosis has not yet been definitively confirmed. As a rule, indications for emergency surgical intervention appear already at the first stages of diagnosis, according to the main ultrasound criteria. The mortality rate averages 3–4%.
Conclusion. The data obtained are approximately comparable with data obtained by other authors. In general, the literature notes that among all patients with pancreatitis, the acute form of the disease predominates. However, in terms of mortality, the results we obtained were slightly lower compared to the results for the country as a whole.
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Volatile organic compounds as potential biomarkers for the diagnosis of digestive diseases. A review
Abstract
Diseases of the digestive system are very common among the population around the world. Diagnosis of the diseases of this group is expensive and often invasive, which greatly limits its accessibility to the population. Increasing the time of disease development before diagnosis increases the risk of complications and adverse outcomes. The use of volatile organic compounds (VOC) as a biomarker is becoming increasingly popular due to the accuracy and ease of use. The article examines the available analytical platforms of VOCs for detecting changes in the state of the digestive system, assesses their strengths and weaknesses, provides examples of VOC assessment tool for the diagnosis of certain diseases of the digestive system – inflammatory bowel diseases, colorectal cancer, infectious diarrhea and celiac disease.
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Multicomponent phytopharmaceutical Dipana for the treatment of hepatobiliary disorders. A review
Abstract
Hepatobiliary disorders contribute significantly to the structure of morbidity, causes of disability and mortality of the world’s population. Therefore, the search for and development of effective and safe hepatoprotective agents for the pharmacotherapy thereof remains a problematic issue. This article presents a pharmacological profile for each of the active ingredients of the composite phytopharmaceutical Dipana, and reviews the evidence for its effectiveness and safety in chronic hepatobiliary disorders.
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Mechanisms of high cardiovascular risk in patients with nonalcoholic fatty liver disease
Abstract
Aim. To optimise the curation of patients with a comorbid course of nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease (CVD) to explore pathogenetically-based targets of high cardiovascular risk (CVR) formation.
Materials and methods. An open comparative study was conducted with the formation of a cohort of 126 patients with comorbid course of NAFLD and CVD with different stages of liver fibrosis, who were divided into comparison groups according to SCORE-2 and SCORE-2-OR. Collection of complaints, medical and life history, examination, general laboratory investigations and examination of hormonal status, abdominal ultrasound, EchoCG and liver elastometry to assess the severity of fibrosis were performed. Work with the study data and graphical analysis was performed using Microsoft Office 2019 software package statistical analysis using STATISTICA 12.0.
Results. SCORE-2 risk increased with increasing age of patients (z=-5.29; p<0.01). The most common non-cardiovascular co-morbidities in the study sample were cholelithiasis in 35 (66.78%) patients. Soluble leptin receptor levels were lower (z=-8.60; p<0.01) and leptin resistance index was higher (z=-5.95; p<0.01) in the higher cardiovascular group. Corresponding data were also obtained when the changes in insulin resistance index were calculated and analysed (z=-2.15; p<0.01). Fibrosis stage was higher, in patients with higher CVR (z=-3.488; p<0.01), while no statistically significant difference in steatosis level was recorded. According to transient elastometry, patients taking statins had lower levels of fibrosis (z=-3.747; p<0.01) and hepatic steatosis (z=-3.379; p<0.01).
Conclusions. The most common pathology is arterial hypertension. Gallstone disease and type 2 diabetes mellitus are often found in patients with a comorbid course. The risk of comorbid pathology and CVD increases with age. Formation of advanced stages of liver fibrosis, hyperinsulinaemia and leptin resistance phenomenon are associated with higher CVR according to SCORE-2 and SCORE-2-OR. The syndrome of increased intestinal permeability is a possible mechanism of increased CVD in patients with NAFLD.
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Known and unknown hymecromone. A review
Abstract
Hymecromone (4-MU) is a recognized agent currently used in clinical practice. Since 1960, hymecromone has been used in many countries as a choleretic and cholespasmolytic, a drug approved for use in humans with biliary tract disorders. The review presents both traditional European and Russian studies of the selective antispasmodic and choleretic properties of hymecromone, due to which hymecromone is the drug of choice for the treatment of biliary tract diseases, as well as new fundamental and clinical studies of numerous pleiotropic effects of 4-MU associated with inhibition of hyaluronic acid and many other properties of this exciting molecule. These include antibacterial, antiviral, and nonspecific anti-inflammatory effects. Positive results have been demonstrated in carbohydrate and lipid metabolism disorders, autoimmune diseases, as well as liver, heart, and kidney diseases. Numerous in vitro and in vivo studies have been presented in pancreatic, prostate, skin, esophagus, breast, liver, ovary, bone cancers, metastatic lesions, leukemia, autoimmune and inflammatory diseases. Hymecromone is indicated not only as a choleretic and cholespasmolytic but also as a choleseptic in cholangitis and chronic cholecystitis, including opisthorchiasis, which does not disagree with its label. Odecromone® (hymecromone, tablets 200 mg) is available on the Russian market; it replaced the originator drug and is its fully equivalent generic.
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Promomed Pharmaceutical Company Wins an Award at Smartpharma® Awards 2024
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