Vol 19, No 6 (2017)

Venous thromboembolic events (VTE) are one of the leading causes of maternal morbidity and mortality all over the world. The main methods of thromboprophylaxis include early mobilization of patients, dehydration treating, applying elastic and pneumocompression and using anticoagulant therapy. It is preferable to use low molecular heparins (LMH) due to their safety. Considering the amount of studies conducted, bemiparin and enoxaparin are the better studied LMH to be used in VTE prophylaxis. It is known that all current treatment protocols recommend using VTE after childbirth to lower the frequency of thromboembolic events in postpartum period.

The article summarizes the published literature and personal experience on using immunotherapy intreatment of relapsing genitourinary tract infections and associated diseases. The article presents data on incidence, social significance, frequency and causes of relapses. Chemical and immunopharmocological characteristics and dosing regimen of Polyoxidoniumare also discussed.The results of personal investigations and of other authors’ studies of using Polyoxidonium in combination therapy for genitourinary tract infectionsare presented and recommendations on using immunotherapy are given. The author concludes that Polyoxidonium® is effective in genitourinary tract infections treatment.

Infection caused by Zika virus is wide-spread in Africa, South-East Asia and on the Pacific Islands; breakouts are noticed on the American continent. Zika virus is transmissible due to Aedes mosquitoes bites; vertical (diaplacental) and sexually transmitted infection is proved. Clinical implications of Zika virus are developed at 20-25% of patients and include hives, joint pain and conjunctivitis. Zika virus is associated with genuine microcephaly, intracranial calcification, antenatal fetal death and Guillain-Barré syndrome progression. Since mosquito′s bite and before clinical implications occurrence, incubation stage lasts 2-14 days; length of disease is about 7 days. Zika virus infection is diagnosed by means of polymerase chain reaction and blood serological test. To detect intrauterine infection series of ultrasound investigation and diagnostic amniocentesis are carried out. There is no specific treatment for Zika virus infection, as well as preventive vaccine.

The article outlines the main provisions of the recommendations of the American Society of Clinical Oncology for primary and secondary prevention of cervical cancer by vaccination and screening programs.