Vol 17, No 1 (2015)


Arterial hypertension and cognitive function

Ostroumova O.D., Dudaev V.A., Galeeva N.Y.


The article presents the definition, classification and pathogenetic mechanisms of cognitive impairment in patients with arterial hypertension (AH). Discusses the literature on the relationship of hypertension with risk of dementia. The possibilities of antihypertensive therapy in the prevention of dementia. Discussed in detail the results of the study Syst-Eur (Systolic Hypertension in Europe), in which the calcium antagonist (CA) nitrendipine ± enalapril reduced the risk of developing dementia, including Alzheimer's disease, new cases, 50%. Neuroprotective action mechanisms are considered as a whole and AK nitrendipine in particular.
Consilium Medicum. 2015;17(1):6-10
pages 6-10 views

Preimushchestva fiksirovannoy kombinirovannoy antigipertenzivnoy terapii u bol'nykh s tserebrovaskulyarnoy patologiey: fokus na kombinatsii «bisoprolol + amlodipin»

Evdokimova A.G., Markova L.I., Evdokimov V.V., Arkad’eva G.V.


The advantages of a fixed combination antihypertensive therapy in patients with cerebrovascular disease: focus on the combination of «bisoprolol and amlodipine»
Consilium Medicum. 2015;17(1):11-17
pages 11-17 views

Efficacy and safety in clinical practice fosinopril

Stryuk R.I.


Diseases of the cardiovascular system, including the leading place is occupied arterial hypertension (AH), making the most significant contribution to the statistics of fatal and disabling complications in the industrialized world, including in Russia. For the treatment of hypertension, according to domestic and European recommendations, 5 main groups of drugs, are applied including a significant role for blockers of the renin-angiotensin-aldosterone system. Among the angiotensin converting enzyme inhibitors deserved place on clinical effectiveness, organo properties and safety profile belongs fosinopril - lipophilic drug with a dual route of elimination. These properties fosinopril have sufficient evidentiary basis, and despite the large variety of drugs in this group, fosinopril has its own niche in the treatment of hypertensive patients, including those with concomitant chronic kidney disease, chronic heart failure, and has future prospects.
Consilium Medicum. 2015;17(1):18-21
pages 18-21 views

Acetylsalicylic acid in hypertensive patients at high risk

Vorobyeva N.M.


The following review discusses the efficacy of aspirin in hypertensive patients at high risk for primary prevention of cardiovascular disease. Considered in detail are the results of the study of NOT, performed in hypertensive patients and the benefits of low-dose aspirin versus placebo for the primary prevention of myocardial infarction and reduce the incidence of the combined endpoint (myocardial infarction, stroke, cardiovascular death) are presented.
Consilium Medicum. 2015;17(1):22-26
pages 22-26 views

The clinical picture, current options for therapy of hypertensive crises

Gurevich M.A., Gorbunova E.M.


Modern data on clinic variants of the course, complications, differentiated treatment of hypertensive crises.
Consilium Medicum. 2015;17(1):27-29
pages 27-29 views

Aggravation of coronary heart disease: the balance of risk and the risk of disease treatment

Braznik V.A., Zateyshchikov D.A.


This review describes current approaches to the treatment of patients who have had an episode of acute ischemic heart disease. Summarizes studies of oral direct inhibitors of hemostasis in this pathology. The only drug of this group rivaroxaban, despite a slight increase in the frequency of bleeding, has demonstrated efficacy in reducing total mortality in thesepatients. Particular attention is given today interventional procedures, which may also serve as a source of additional problems, especially stent thrombosis. Rivaroxaban has proved effective in reducing the frequency of this complication.
Consilium Medicum. 2015;17(1):30-35
pages 30-35 views

Prehospital appointment of ticagrelor in patients with myocardial infarction and ST segment elevation (abstract)

Komarov A.L., Shakhmatova O.O.


Материал подготовлен А.Л.Комаровым (д-р мед. наук, вед. науч. сотр. лаб. атеротромбоза НИИ кардиологии ФГБУ РКНПК) и О.О.Шахматовой (канд. мед. наук, мл. науч. сотр. лаб. атеротромбоза НИИ кардиологии ФГБУ РКНПК) по статье Montalescot G, van't Hof AW, Lapostolle F et al. Prehospital ticagrelor in ST -segment elevation myocardial infarction. N Engl J Med 2014; 371: 1016-27
Consilium Medicum. 2015;17(1):36-40
pages 36-40 views

Prospects for personalized utilization of non-vitamin K anticoagulants based on the assessment of pharmacokinetics in patients with atrial fibrillation

Kryukov A.V., Sychev D.A., Saveleva M.I., Ryabova A.V., Ilina E.S., Yurovsky A.Y.


The article is devoted to the actual problem of non-vitamin K anticoagulants application (NOAC) for secondary stroke prevention in patients with atrial fibrillation. Therapeutic drug monitoring is considered a promising tool for personalized anticoagulation that allows to prevent the development of complications associated with NOAC administration.
Consilium Medicum. 2015;17(1):41-43
pages 41-43 views

Approaches to the choice of a statin to treat patients on an outpatient basis

Ostroumova O.D., Dudaev V.A., Schukina G.N.


The paper presents an algorithm of examination of the patient to decide on the appointment of statins for the treatment of dyslipidemia and atherosclerosis. The criteria of the effectiveness of statin therapy. The advantages of atorvastatin and rosuvastatin. We discuss the choice of a statin for the treatment of selected patients with changes in blood lipid spectrum.
Consilium Medicum. 2015;17(1):44-49
pages 44-49 views

Safety monitoring of medicines in health facilities: problems and perspective of development

Morozova T.E., Hoseva E.N., Andruschishina T.B., Vartanova O.A.


Legislation in the field of drugs in the Russian Federation fixed responsibility of health professionals to identify, register, timely informing regulators of cases of adverse drug reactions. Despite the improvement of the pharmacovigilance system in Russia, the activity of health professionals to monitor the efficacy and safety of the drugs remains low. The article presents guidelines for creating at medical institutions effective pharmacovigilance system.
Consilium Medicum. 2015;17(1):50-53
pages 50-53 views

Lifestyle modification, training and self-control as important components of diabetes treatment and improvement of patients life quality

Volkova E.A., Vorokhobina N.V., Malygina O.F.


The article deals with the problem of lifestyle modification in patients with diabetes mellitus, the connection between type 2 diabetes and cardiovascular disease, the causes of unsatisfactory noncompliance many patients with diabetes with regard to lifestyle changes and recommended medical treatment. The role of health professionals in the treatment of patients, the value of structured training programs for the treatment of type 2 diabetes patients is emphasized the need for education in schools diabetic patients, the importance of self-control and an individual approach to each patient specialists to improve the quality of life.
Consilium Medicum. 2015;17(1):54-62
pages 54-62 views

Differential diagnosis of chest pain: in focus digestive diseases

Trukhan D.I.


The problem of proper diagnostic interpretation of chest pain is one of the most complex and urgent internal diseases. The article describes the features of pain in various diseases of the digestive system, covered issues of diagnosis and differential diagnosis.
Consilium Medicum. 2015;17(1):63-67
pages 63-67 views

Iatrogenic risk factors and correction of dyslipidemia after liver transplantation

Kosmacheva E.D., Babich A.E.


The article analyzes information of the prevalence, causes and mechanisms of development of dyslipidemia in patients after liver transplantation. The authors integrate data from domestic and foreign literature about priorities of choice of lipid-lowering drugs and possible changes in patterns of immunosuppressive drug therapy to reduce the risk of onset and progression of cardiovascular disease in patients who were underwent orthotopic liver transplantation.
Consilium Medicum. 2015;17(1):68-71
pages 68-71 views
pages 72 views

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